Web4 aug. 2016 · Proteins that bind DNA or RNA are usually put in different categories, but researchers recently showed how the p53 protein has the capacity to bind both and how … Web12 apr. 2024 · PITAR interaction with TRIM28 RNA stabilized TRIM28 mRNA, which resulted in increased TRIM28 protein levels, enhanced p53 ubiquitination, and attenuated DNA damage response. While PITAR silencing inhibited the growth of WT p53 containing GSCs in vitro and reduced glioma tumor growth in vivo, its overexpression enhanced the tumor …
Unit 1 proteins - Protein notes - How do we function? We are
WebCharacterizing protein–protein interactions through methods such as co-immunoprecipitation (co-IP), pull-down assays, crosslinking, label transfer, and … Web9 mrt. 2024 · Interactions between proteins and their ligands can influence protein conformation and, hence, thermal stability. The magnitude of change in thermal stability … can we visit rashtrapati bhavan
DNA interactions: understanding what your DNA is up to
Web15 mrt. 2011 · Sliding on the DNA may be common to proteins other than DNA clamps before they bind to their specific target sequences. Both one-dimensional diffusion of … Web14 apr. 2024 · RNA-binding motif protein 14 (RBM14) is upregulated in a variety of tumors. However, the expression and biological role of RBM14 in lung cancer remain unclear. Chromatin immunoprecipitation and PCR were carried out to measure the levels of sedimentary YY1, EP300, H3K9ac, and H3K27ac in the RBM14 promoter. Co … Web11 apr. 2024 · The Ku heterodimer, composed of subunits Ku70 and Ku80, is known for its essential role in repairing double-stranded DNA breaks via non-homologous end joining (NHEJ). We previously identified Ku70 S155 as a novel phosphorylation site within the von Willebrand A-like (vWA) domain of Ku70 and documented an altered DNA damage … can we vlookup two columns