WebMar 4, 2024 · All the known dynamin family proteins perform cellular functions by associating with a target membrane. Classical dynamins contain a pleckstrin homology (PH) domain responsible for membrane binding ().Drp6 associates with nuclear envelope and regulates nuclear remodeling in Tetrahymena.However, Drp6 like other DRPs lacks a PH … WebJan 21, 1997 · Shortly after the initial purification of dynamin from bovine brain, a cDNA encoding the full rat brain dynamin was isolated by Obar et al. using an anti-dynamin polyclonal antibody.Subsequently, sequence analysis of the D. melanogaster shibire gene revealed an 81% similarity to the brain dynamin cDNA (8, 9).The finding that dynamin is …
Structural Insights into the Mechanism of Dynamin …
WebAug 5, 1997 · An SH3 domain-containing protein that has been strongly implicated in the synaptic vesicle cycle via its interactions with dynamin I and synaptojanin is … WebApr 22, 2024 · The regulation of this cycle is critical for biological function of all dynamin family proteins. The vast array of protein post-translational modifications provides the cell a dynamic and rapid way of regulating various essential processes in response to cellular stimuli. The proteins of this family undergo a variety of post-translational ... diamond resorts owner
Evolutionary linkage between eukaryotic cytokinesis and …
WebDynamin is a protein required for vesicle formation during synaptic vesicle endocytosis (SVE) and for clathrin-mediated endocytosis. It is part of a family of large guanosine triphosphatases (GTPases), including classical dynamins, dynamin-like protein, optic atrophy 1 (OPA1), and mitofusin. Dynamin readily self-assembles into rings and helices ... WebAug 1, 2002 · Dynamin is a multidomain GTPase (Fig. 1 a) whose domain structure includes the amino-terminal GTPase domain, the middle domain, the pleckstrin homology (PH) domain, the GTPase effector domain (GED), and the carboxy-terminal proline/arginine-rich domain (PRD).The highest degree of sequence identity among dynamin family … WebDynamin-like proteins (DLPs) are a family of membrane-active proteins with low sequence identity. The proteins operate in different organelles in eukaryotic cells, where they trigger vesicle formation, membrane fusion, … cisco cucm phone registration rejected